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Performance Peptides
Performance peptides are designed to build lean muscle, reduce body, decrease recovery time from a workout and raise energy levels. They work primarily by increasing growth hormone.
Performance Peptide Fundamentals
GHRH - (Growth Hormone Releasing Hormone)
GHRH is secreted from the hypothalamus, and it stimulates the production and release of growth hormone (GH) secretion by binding to the growth hormone-releasing hormone receptor (GHRH-R) of the somatotroph cells in the anterior pituitary gland.
GHRHs directly stimulate the pituitary gland, telling it to produce and release more growth hormone.
GHRP - (Growth Hormone Releasing Peptide)
GHRPs work through ghrelin receptors, telling the body to release more growth hormone.
GHRPs work through several mechanisms to increase GH secretion:
Ghrelin Mimetic:
GHRPs bind to the ghrelin receptor (GHS-R), stimulating the hypothalamus and pituitary gland to release growth hormone. It essentially mimics ghrelin, enhancing its natural effects on GH secretion.
Somatostatin Inhibition:
Somatostatin is a hormone that inhibits the release of GH. GHRP suppresses somatostatin levels, allowing for greater and more consistent growth hormone secretion.
Pulse Stimulation:
GHRPs induce a pulsatile release of GH, which is similar to the body’s natural secretion patterns, leading to better efficacy and fewer risks of desensitization compared to constant stimulation.
GHRH & GHRP Synergy Is Key
Combining a GHRP with GHRH is ideal for maximizing growth hormone levels.
The key to optimizing your performance (muscle gain and fat loss) is to combine or stack GHRH and GHRP peptides. Combining them provides more than double the effect of either alone due to the synergies that they have with each other.
Featured Performance Peptides
GHRH - Growth Hormone Releasing Hormones
CJC-1295 No DAC
CJC-1295 With DAC
CJC-1295 With DAC
Modified GRF (CJC-1295 No DAC) is a truncated peptide analogue of growth hormone releasing hormone (GHRH).
First developed in the 1980s, research studies with mod GRF have shown it to improve muscle repair and growth, accelerate wound healing, strengthen bones, increase fat burning, and improve metabolism. It may also have beneficial effects on blood sugar regulation and the immune system.
CJC-1295 With DAC
CJC-1295 With DAC
CJC-1295 With DAC
CJC-1295 with DAC is a synthetic analogue of growth hormone releasing hormone (GHRH) that increases plasma levels of growth hormone and insulin-like growth factor 1 (IGF-1). This peptide consists of 29 amino acids and is a modified version of growth hormone-releasing hormone (GHRH). Its primary function is to prompt the pituitary gland to release more HGH, which plays a vital role in various physiological processes.
CJC-1295 can enhance muscle growth, healing of injuries, and reduce body fat.
Tesamorelin
Tesamorelin
Tesamorelin
Tesamorelin, a synthetic peptide comprising 44 Amino acids, is a growth-hormone-releasing hormone (GHRH) analogue. Tesamorelin mimics the action of an endogenous hormone in the body known as GHRH. It binds with the hormone releasing hormone receptors (GHRHr) located in the anterior pituitary gland. This triggers the release of GH.
The benefits of Tesamorelin are muscle gain, fat loss, and increased bone density.
Sermorelin
Tesamorelin
Tesamorelin
Sermorelin is a synthetic peptide that mimics the action of natural growth hormone-releasing hormone (GHRH) and can be used to increase GH levels in the body.
Sermorelin can enhance muscle growth, promote efficient wound healing, reduce body fat, improve sleep quality, enhance brain functioning, and support cardiovascular health.
GHRP - Growth Hormone Releasing Peptides
Ipamorelin
Ipamorelin
Ipamorelin
Ipamorelin is a pentapeptide and a ghrelin mimetic with growth hormone (GH) releasing activity. By mimicking ghrelin, Ipamorelin selectively binds the same GHSR-1a receptor as GHRP-2, and GHRP-6 . This interaction with GHSR-1a leads to a GH release from the pituitary gland, which can influence several anabolic processes including appetite regulation, fat processing, and overall energy usage.
Ipamorelin does not release ACTH or cortisol in levels significantly different from those observed following GHRH stimulation.
GHRP-2
Ipamorelin
Ipamorelin
GHRP-2, a growth hormone-releasing peptide, more commonly known as Pralmorelin, is a synthetic growth hormone secretagogue (GHS) that binds to the ghrelin/growth hormone secretagogue receptor (GHS-R), which results in an increased natural secretion of growth hormone (GH) from the anterior pituitary gland.
It is a hexapeptide containing 6 amino acids and has been shown in research trials to improve muscle growth, regulate the immune system, and improve sleep cycles.
GHRP-2 also works by suppressing the release of somatostatin, which is also called a growth hormone-inhibiting hormone (GHIH). As the somatostatin levels fall, the negative feedback system won’t remain intact, and growth hormone (GH) levels would spike substantially.
GHRP-2 also seems to slightly increase the serum levels of hormones such as prolactin, ACTH, and cortisol.
GHRP-6
Ipamorelin
Hexarelin
GHRP-6, another growth hormone-releasing peptide, is also a synthetic growth hormone secretagogue (GHS). It contains 28 amino acids in a specific sequence.
Although GHRP-6 also stimulates the release of growth hormone (GH), it follows a slightly different pathway. GHRP-6 activates the ghrelin by binding to ghrelin receptors, which sends signals to the anterior pituitary gland for an increased release of growth hormone (GH). GHRP-6 also inhibits the expression of somatostatin. As somatostatin falls, no signaling pathway can regulate growth hormone levels (GH). Hence, the blood levels of growth hormone (GH) increase substantially. Increased growth hormone (GH) release by GHRP-6 also leads to a higher release of insulin growth factor-1 (IGF-1) by the liver. IGF-1 is an anabolic hormone, which is critical in growth and development.
Hexarelin
Hexarelin
Hexarelin
Hexarelin, also called Examorelin, is a synthetic analogue of ghrelin and is closely related to GHRP-6. In fact, Hexarelin and GHRP-6 differ from each other only slightly thanks to the addition of two menthyl groups to GHRP-6.
Hexarelin, like many ghrelin analogues, is orally and sublingually active and highly selective.
MK-677
Hexarelin
MK-677
MK-677, is a orally bio-active, selective agonist of the ghrelin receptor.
Research shows that MK-677 increases the natural secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), but does not affect cortisol levels.
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HGH
Released by the pituitary gland in the brain human growth hormone (HGH) is considered the hormone of youth. It is responsible for the rapid growth and development of children and is also responsible for their astounding healing powers. Once released by the pituitary gland it is quickly taken in by the liver prompting the liver to release the growth factor called IGF-1. It is IGF-1 that goes to the individual cells and prompts cell rejuvenation and tissue repair throughout the entire body. HGH and IGF-1 regulate the muscle/fat ratio by increasing lean muscle and decreasing fat. They also strengthen the cardiovascular and immune systems, improve enzyme production, enhance energy levels, strength and stamina, improve bone density, decrease cholesterol, enhance sexual function and libido, improve sleep, increase sense of well-being, and more.
Once adulthood is reached HGH becomes the repair and rejuvenation hormone. It works throughout life to help maintain brain function, muscle tone, bone strength, immune function, the integrity of the skin and hair, and in fact it plays a supportive role in about every system in the body.
Unfortunately, the body's production of HGH diminishes with age.
GH - Growth Hormone Boosting Peptides
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191 is a small, synthetic piece of natural human growth hormone (hGH). It is often referred to as the “lipolytic fragment” for its ability to boost fat loss.
It has been shown to help lowers blood sugar levels and promote cartilage healing without increasing long bone growth, increasing IGF-1 levels, or altering insulin sensitivity.
AOD9604
HGH Fragment 176-191
HGH Fragment 176-191
AOD9604 is a modified version of the hGH fragment 176-191 peptide (contains a di-sulfide bridge) and thus a derivative of human growth hormone (hGH).
Originally developed as a lipolytic (fat burning) compound, AOD9604 has shown benefit in studies of heart disease, osteoarthritis/cartilage repair, and metabolic syndrome. AOD9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis in animal studies.
Somatropin
HGH Fragment 176-191
Somatropin
Human growth hormone (HGH), also called somatropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases. The pituitary gland has two parts – a front (anterior) and a back (posterior) lobe. The front lobe produces HGH.
There are two types of HGH: the kind your body naturally makes and a synthetic version.
HGH boosts a hormone called insulin-like growth factor-1 (IGF-1), which works like insulin to control your blood sugar levels.
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IGF-1
IGF-1 (Insulin-like Growth Factor-1), also known as Somatomedin C is a 70 amino acid protein that is produced mainly in the liver in response to human growth hormone. IGF-1 is only one of the body's many growth factors. It is a part of the insulin super-family.
Growth factors function similarly to hormones, however hormones usually send long distance messages and the growth factors usually send local messages.
They regulate cell growth and control the metabolic processes. They enable the cells in the hormonal, immune, and nervous systems to communicate and coordinate their growth, death, regeneration, and functioning. Cell reproduction slows down as we age. Unless they are prompted by the growth factors they will go into a resting phase.
IGF-1 is responsible for a wide range of cellular functions and is required for normal growth and health maintenance. These functions include cellular differentiation, transformation, and apoptosis suppression.
IGF-1 helps to transfer glucose through the cell membranes and helps to supply the raw materials that cells need for growth and repair. It also regulates cell growth by moving the cells from the resting phase to the active phase of its cycle and it increases the cell's ability to complete DNA synthesis.
IGF-1 Boosting Peptides
IGF-1-LR3
IGF-1-LR3
IGF-1-LR3
IGF-1 LR3 (insulin-like growth factor-1 long arginine 3) is a synthetic, modified construct of insulin-like growth factor-1. Because IGF-1 LR3 does not bind to IGF-1 binding proteins very well, it remains active up to 120 times longer than standard IGF-1. This results in improved half-life for the peptide and thus increased activity. IGF-1 LR3 enhances cell division and growth, boosts fat metabolism, and increases muscle repair and hypertrophy by inhibiting myostatin.
IGF-1 LR3 and IGF-1 DES are both modifications of the base protein IGF-1. Here are the differences:
IGF-1 LR3: Has a longer half-life, is less sensitive, and is more potent. It is used for overall body effects.
IGF-1 DES: Has a shorter half-life (20-30 minutes) and is delicate, making it ideal for targeted muscle development at the injection site.
IGF-1-DES
IGF-1-LR3
IGF-1-LR3
IGF-1 DES is a truncated, natural version (splice variant) of insulin-like growth factor-1. Naturally found in the brain, breast milk, and uterine tissue, IGF-1 DES stimulates hypertrophy and hyperplasia of a number of different cell lines. Research has shown this version of the protein to be more potent than standard IGF-1, mostly as a result of its enhanced bioavailability. Research shows that it helps to maintain the health of synaptic connections in the central nervous system and, like all IGF-1, promotes the repair of muscle and connective tissue.
IGF-1 LR3 and IGF-1 DES are both modifications of the base protein IGF-1. Here are the differences:
IGF-1 LR3: Has a longer half-life, is less sensitive, and is more potent. It is used for overall body effects.
IGF-1 DES: Has a shorter half-life (20-30 minutes) and is delicate, making it ideal for targeted muscle development at the injection site.
PEG-MGF
IGF-1-LR3
PEG-MGF
PEG-MGF, or PEGylated Mechano Growth Factor, is a modified version of MGF, itself a modified form of IGF-1. The pegylation process involves attaching polyethylene glycol (PEG) to the MGF molecule, which extends the peptide's half-life, allowing it to remain active in the body for a longer period. This modification enhances the stability and bioavailability of MGF, making PEG-MGF more effective in promoting muscle growth and recovery compared to its natural counterpart. By prolonging the activity of MGF in the body, PEG-MGF enables a sustained and amplified muscle repair process, which can lead to more significant gains in muscle mass and strength.
Research has shown it to lower cholesterol and total body fat, boost immune function, and improve rates of wound healing.
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